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![]() ![]() As a result, the amount of oxygen in the blood decreases, whereas the carbon dioxide level increases. Dead spaces can severely impact breathing, because they reduce the surface area available for gas diffusion. ![]() ![]() Both produce dead space or shunts, regions of ineffective lung tissue. This difference between the amounts of air and blood reaching the lungs is referred to as ventilation/perfusion (V/Q) mismatch. At times, however, there is a mismatch between the amount of air (ventilation, V) and the amount of blood (perfusion, Q) in the lungs. These capillaries and arteries are not always in use but are ready if needed. As cardiac output increases, the number of capillaries and arteries that are perfused (filled with blood) increases. This is because of a phenomenon called recruitment, which is the process of opening airways that normally remain closed when cardiac output increases. It is also independent of cardiac output. Pulmonary circulation pressure is very low compared to that of the systemic circulation. Lung procedures, tests & treatments.Ĭenters for Disease Control and Prevention. Morphometric analysis of explant lungs in cystic fibrosis. Bronchiolitis obliterans.īoon M, Verleden SE, Bosch B, et al. National Center for Advancing Translational Sciences/National Institutes of Health. Respiratory syncytial virus infection and bronchiolitis. Overview and challenges of bronchiolar disorders. Swaminathan AC, Carney JM, Tailor TD, Palmer SM. The impact of cold on the respiratory tract and its consequences to respiratory health. The physiological basis of pulmonary gas exchange: implications for clinical interpretation of arterial blood gases. The role and importance of club cells (Clara cells) in the pathogenesis of some respiratory diseases. Rokicki W, Rokicki M, Wojtacha J, Dżeljijli A. ![]() Elastin in lung development and disease pathogenesis. A unique cellular organization of human distal airways and its disarray in chronic obstructive pulmonary disease. The comparison of the lengths and diameters of main bronchi measured from two-dimensional and three-dimensional images in the same patients. ![]()
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